Finasteride

描述

Finasteride · CAS 98319-26-7 · C23H36N2O2. UNII 57GNO57U7G. 熔點：252-254 °C; 熔點：252 – 254 °C; 溶解性：1.98e-03 g/L.

鑑定資訊

計算描述符

物理與化學性質

物理描述與處理注意事項

• Solid
• White to off-white crystalline solid
• Slightly soluble
• Freely sol in chloroform, DMSO, ethanol, methanol, n-propanol; sparingly sol in propylene glycol, polyethylene glycol 400; very slightly sol in 0.1N hydrogen chloride, 0.1N sodium hydroxide, water.
• 52.8 [ug/mL] (The mean of the results at pH 7.4)
• 198.1 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID3020625]

GHS 危害分類

文獻記載用途

• Medication: Treatment of benign prostatic hypertrophy
• Use (kg; approx.) in Germany (2009): >250
• Consumption (g per capita; approx.) in Germany (2009): 0.00305
• Consumption (g per capita) in the USA (2002): 0.00143
• For the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate to: Improve symptoms, reduce the risk of acute urinary retention, reduce the risk of the need for surgery including transurethral resection of the prostate. Also used for the stimulation of regrowth of hair in men with mild to moderate androgenetic alopecia (male pattern alopecia, hereditary alopecia, common male baldness).
• Finasteride is a 5-alpha reductase inhibitor used to treat symptoms of benign prostatic hypertrophy and male pattern baldness. Finasteride is associated with a low rate of transient serum aminotransferase elevations, but has yet to be linked to instances of clinically apparent, acute liver injury.

同義詞

finasteride; 98319-26-7; Proscar; Propecia; Finastid; Prostide; Chibro-Proscar; MK-906; Finasterida; Finpecia; Finasteridum; MK 906; DTXSID3020625; N-tert-Butyl-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide; MK906; (5alpha,17beta)-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide

常見問題

Finasteride 的 CAS 登錄號與分子式為何？

CAS 98319-26-7; 分子式 C23H36N2O2; 分子量 — g/mol.

Finasteride 還有哪些其他名稱？

finasteride, 98319-26-7, Proscar, Propecia, Finastid, Prostide.

Finasteride 是否列為有害物質？

通報的危害說明: H302, H360, H372, H410.

Finasteride 的主要物理性質為何？

熔點：252-254 °C; 熔點：252 – 254 °C; 溶解性：1.98e-03 g/L; LogP: 3.03.

本頁資料取自 PubChem（美國國家醫學圖書館）與 Wikidata。等級專屬資料 — 含量、水分、粒徑、包裝、保存期限 — 隨每批附於 COA，本頁不公布。

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